Afelimomab

From Wikipedia, the free encyclopedia

This article does not cite any references or sources.
Please help improve this article by adding citations to reliable sources. Unverifiable material may be challenged and removed. (July 2007)

Afelimomab^?
Therapeutic monoclonal antibody
Source	Mouse
Target	TNFα
Identifiers
CAS number	156227-98-4
ATC code	L04AA16
PubChem	?
Chemical data
Formula	?
Mol. mass	?
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Afelimomab (also known as Fab 2 or MAK 195F) is an anti-TNF-α monoclonal antibody. Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis.

This monoclonal antibody-related article is a stub. You can help Wikipedia by expanding it.

v • d • e

Immunomodulators - Immunosuppressants - Immunosuppressive drugs (L04)

Extracellular

Antibodies	CD3 (Muromonab-CD3, Teplizumab, Visilizumab) · CD4 (Keliximab, Zanolimumab) · CD11a (Efalizumab) · CD20 (Ocrelizumab, Pascolizumab) · CD23 (Lumiliximab) · IL-2/CD25 (Basiliximab, Daclizumab, Inolimomab) · CD40 (Teneliximab) · CD62L/L-selectin (Aselizumab) · CD147/Basigin (Gavilimomab, Ziralimumab) · CD154 (Ruplizumab) BLyS (Belimumab) · Complement component 5 (Eculizumab) · CTLA-4 (Ipilimumab) · CAT (Metelimumab) · Immunoglobulin E (Omalizumab) · Integrin (Natalizumab) · Interleukin 5 (Mepolizumab) · Interleukin-6 receptor (Tocilizumab) · TNFs (Infliximab, Adalimumab, Certolizumab pegol, Afelimomab, Golimumab) · LFA-1 (Odulimomab) other monoclonal: Atlizumab, Atorolimumab, Bertilimumab, Cedelizumab, Clenoliximab, Dorlimomab aritox, Dorlixizumab, Elsilimomab, Erlizumab, Faralimomab, Fontolizumab, Galiximab, Gantenerumab, Gomiliximab, Ibalizumab, Lebrilizumab, Lerdelimumab, Maslimomab, Morolimumab, Nerelimomab, Otelixizumab, Pexelizumab, Reslizumab, Rovelizumab, Siplizumab, Talizumab, Telimomab aritox, Toralizumab, Ustekinumab, Vapaliximab, Vepalimomab, Zolimomab aritox Polyclonal: Anti-thymocyte globulin - Anti-lymphocyte globulin

-cept (Fusion protein)	Abatacept, Aflibercept, Alefacept, Belatacept, Rilonacept, TNF inhibitor (Etanercept)

IL-1 receptor antagonists	Anakinra

Intracellular

Antimetabolites	purine synthesis inhibitor: Azathioprine, Mycophenolic acid pyrimidine synthesis inhibitor: Leflunomide, Teriflunomide antifolate: Methotrexate

Macrolides/ other IL-2 inhibitors	diminished production, FKBP/Cyclophilin/Calcineurin: Tacrolimus, Ciclosporin, Pimecrolimus diminished response, mTOR: Sirolimus, Deforolimus, Everolimus, Temsirolimus, Zotarolimus other: Abetimus, Gusperimus

TNF-α inhibitor	Thalidomide

v • d • e Mouse monoclonal antibodies ("-o-")

"-govo-" (ovarian tumor)	Abagovomab, Igovomab, Oregovomab

"-limo-" (immune system)	Afelimomab, Dorlimomab aritox, Elsilimomab, Faralimomab, Gavilimomab, Inolimomab, Maslimomab, Nerelimomab, Odulimomab, Telimomab aritox, Vepalimomab, Zolimomab aritox

"-tumo-" (miscellaneous tumor)	Altumomab, Anatumomab mafenatox, Arcitumomab, Bectumomab, Blinatumomab, Detumomab, Epitumomab, Epitumomab cituxetan, Ibritumomab tiuxetan, Minretumomab, Mitumomab, Naptumomab estafenatox, Nofetumomab merpentan, Pemtumomab, Pintumomab, Satumomab, Taplitumomab paptox, Tositumomab, 3F8

"-leso-" (infectious lesions)	Besilesomab, Fanolesomab, Lemalesomab, Sulesomab

"-ciro-" (cardiovascular)	Biciromab brallobarbital, Imciromab

"-pro-" (prostate tumor)	Capromab

"-baco-" (bacterial)	Edobacomab

"-colo-" (colonic tumor)	Edrecolomab, Nacolomab tafenatox

Retrieved from "http://en.wikipedia.org/wiki/Afelimomab"

Categories: Monoclonal antibody stubs • Monoclonal antibodies

Afelimomab

From Wikipedia, the free encyclopedia

WANT TO ADVERTISE ON ALL OF OVER 11 MILLION SUBPAGES WE HAVE ON THIS SITE FOR UNDER $15? CLICK HERE!