Aselizumab

Aselizumab^?
Therapeutic monoclonal antibody
Source	Human
Target	CD62
Identifiers
CAS number	?
ATC code	?
PubChem	?
Chemical data
Formula	?
Mol. mass	?
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
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Legal status
Routes	?

Aselizumab is an immunosuppressive drug. It binds to CD62L.

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v • d • e

Extracellular

Antibodies	CD3 (Muromonab-CD3, Teplizumab, Visilizumab) · CD4 (Keliximab, Zanolimumab) · CD11a (Efalizumab) · CD20 (Ocrelizumab, Pascolizumab) · CD23 (Lumiliximab) · IL-2/CD25 (Basiliximab, Daclizumab, Inolimomab) · CD40 (Teneliximab) · CD62L/L-selectin (Aselizumab) · CD147/Basigin (Gavilimomab, Ziralimumab) · CD154 (Ruplizumab) BLyS (Belimumab) · Complement component 5 (Eculizumab) · CTLA-4 (Ipilimumab) · CAT (Metelimumab) · Immunoglobulin E (Omalizumab) · Integrin (Natalizumab) · Interleukin 5 (Mepolizumab) · Interleukin-6 receptor (Tocilizumab) · TNFs (Infliximab, Adalimumab, Certolizumab pegol, Afelimomab, Golimumab) · LFA-1 (Odulimomab) other monoclonal: Atlizumab, Atorolimumab, Bertilimumab, Cedelizumab, Clenoliximab, Dorlimomab aritox, Dorlixizumab, Elsilimomab, Erlizumab, Faralimomab, Fontolizumab, Galiximab, Gantenerumab, Gomiliximab, Ibalizumab, Lebrilizumab, Lerdelimumab, Maslimomab, Morolimumab, Nerelimomab, Otelixizumab, Pexelizumab, Reslizumab, Rovelizumab, Siplizumab, Talizumab, Telimomab aritox, Toralizumab, Ustekinumab, Vapaliximab, Vepalimomab, Zolimomab aritox Polyclonal: Anti-thymocyte globulin

-cept (Fusion protein)	Abatacept, Aflibercept, Alefacept, Belatacept, Rilonacept, TNF inhibitor (Etanercept)

IL-1 receptor antagonists	Anakinra

Intracellular

Antimetabolites	purine synthesis inhibitor: Azathioprine, Mycophenolic acid pyrimidine synthesis inhibitor: Leflunomide antifolate: Methotrexate

Macrolides/ other IL-2 inhibitors	diminished production, FKBP/Cyclophilin/Calcineurin: Tacrolimus, Ciclosporin, Pimecrolimus diminished response, mTOR: Sirolimus, Deforolimus, Everolimus, Temsirolimus, Zotarolimus other: Abetimus, Gusperimus

TNF-a inhibitor	Thalidomide

v • d • e Humanized monoclonal antibodies ("-zu-")

"-tuzu-" (tumor)	Alemtuzumab, Bevacizumab/Ranibizumab, Bivatuzumab mertansine, Cantuzumab mertansine, Dacetuzumab, Elotuzumab, Etaracizumab, Etaratuzumab, Gemtuzumab ozogamicin, Inotuzumab ozogamicin, Labetuzumab, Lintuzumab, Matuzumab, Nimotuzumab, Pertuzumab, Sibrotuzumab, Sontuzumab, Tacatuzumab tetraxetan, Trastuzumab, Tucotuzumab celmoleukin

"-lizu-" (immune system)	Aselizumab, Atlizumab, Apolizumab, Cedelizumab, Certolizumab pegol, Daclizumab, Eculizumab, Efalizumab, Epratuzumab, Erlizumab, Fontolizumab, Ibalizumab, Lebrilizumab, Mepolizumab, Natalizumab, Ocrelizumab, Omalizumab, Pascolizumab, Pexelizumab, Reslizumab, Rovelizumab, Ruplizumab, Siplizumab, Talizumab, Teplizumab, Tocilizumab, Toralizumab, Visilizumab

"-bazu-" (bacterial)	Tefibazumab

"-cizu-" (cardiovascular)	Bevacizumab, Tadocizumab

"-neuzu-" (nervous system)	Bapineuzumab

"-toxazu-" (toxin as target)	Urtoxazumab

"-vizu-" (viral infections)	Felvizumab, Motavizumab, Palivizumab, PRO 140

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