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Poly ICLC

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Poly ICLC
Systematic (IUPAC) name
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ATC code L03AX08
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Poly ICLC is an immunostimulant.

It consists of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA.[1]

It is a ligand for toll like receptor-3.[2]

[edit] References

  1. ^ "Definition of poly ICLC - National Cancer Institute Drug Dictionary". Retrieved on 2007-11-13.
  2. ^ Zhu X, Nishimura F, Sasaki K, et al (2007). "Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models". Journal of translational medicine 5: 10. doi:10.1186/1479-5876-5-10. PMID 17295916. 

http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=39559

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